Hydrophobic nano-carrier for lysozyme adsorption

A novel matrix for hydrophobic interaction chromatography and its application in lysozyme adsorption.

A novel 1-naphthylamine (NA) coupled poly(2-hydroxyethyl methacrylate-co-N-methacryloyl-(L)-histidine methyl ester) [NA-PHEMAH] supermacroporous monolithic hydrophobic cryogel was prepared via covalent coupling of NA to PHEMAH for adsorption of lysozyme from aqueous solution. Firstly, PHEMAH monolithic cryogel was prepared by radical cryocopolymerization of HEMA with MAH as a functional comonom...

Adsorption and desorption of lysozyme on thermosensitive nano-sized magnetic particles and its conformational changes

Introduction In recent years, there has been a great interest in the fabrication of stimuli responsive polymer microspheres for technological application and fundamental studies. These stimuli responsive smart and intelligent polymeric materials can respond in shape or volume changes to small external stimuli such as temperature, pH and ionic strength etc [1, 2]. Among these stimuli responsive ...

Quartz Crystal Microbalance Based Hydrophobic Nanosensor for Lysozyme Detection

Modeling surfactant adsorption on hydrophobic surfaces.

Surfactant adsorption on hydrophobic surfaces is of current interest in attempts to solubilize single-wall carbon nanotubes and to render quantum dots biocompatible. A coarse grained method is presented for incorporating a hydrophobic surface into existing liquid force fields by appealing to statistical mechanics and probability theory. The dimensionality problem which arises is overcome with a...

Water adsorption in hydrophobic MOF channels.

We report an investigation of water adsorption in the hydrophobic metal-organic framework Al(OH)(1,4-naphthalenedicarboxylate) by means of molecular simulation. We show how simple molecular models allow us to reproduce the experimental isotherm, and how grand canonical Monte Carlo simulations can help elucidate the question of the thermodynamic nature of the adsorption transition, which turns o...